Product Data Sheet
Nrf2 activator 17
Catalog No. A79531
Nrf2 activator 17 is a potent activator of the Nrf2 signaling pathway, functioning by inhibiting the interaction between Keap1 and Nrf2 with an IC50 of less than 0.1 pM. This compound demonstrates significant biological activity, exhibiting an EC50 of less than 10 µM in HepG2 cells. Nrf2 activator 17 is utilized in research applications focused on oxidative stress, cellular protection, and the study of Nrf2-related pathways in various disease models.
Chemical Information
| Catalog Num | A79531 |
|---|---|
| M. Wt | 517.62 |
| Formula | C29H35N5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3059044-55-9 |
| Synonyms | |
| SMILES | CC1=C2C=CC3=C1N=NN3CCCCOC4CCN(C(N5CCC6=CC=C(C2CC(O)=O)C=C6C5)=O)CC4 |
Biological Activity
| Description | Nrf2 activator 17 is a potent activator of the Nrf2 signaling pathway, functioning by inhibiting the interaction between Keap1 and Nrf2 with an IC50 of less than 0.1 pM. This compound demonstrates significant biological activity, exhibiting an EC50 of less than 10 µM in HepG2 cells. Nrf2 activator 17 is utilized in research applications focused on oxidative stress, cellular protection, and the study of Nrf2-related pathways in various disease models. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
