Product Data Sheet
Keap1-Nrf2 probe
Catalog No. A79536
Keap1-Nrf2 Probe is designed to selectively bind to the Kelch-like ECH-associated protein 1 (Keap1), modulating the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway. By inhibiting Keap1 function, this probe enhances the transcription of antioxidant response elements, promoting cellular defense against oxidative stress. It is valuable for research on oxidative stress-related diseases, drug discovery targeting the Nrf2 pathway, and studying cellular mechanisms involved in stress responses.
Chemical Information
| Catalog Num | A79536 |
|---|---|
| M. Wt | 1093.14 |
| Formula | C48H72N10O19 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2430031-36-8 |
| Synonyms | |
| SMILES | [C@@H](CC1=CC=CC=C1)(NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)NC(C)=O)=O)CC(O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)[C@@H](C)O)=O)=O)CCC(O)=O)=O)C(N[C@@H](CC(C)C)C(N)=O)=O |
Biological Activity
| Description | Keap1-Nrf2 Probe is designed to selectively bind to the Kelch-like ECH-associated protein 1 (Keap1), modulating the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway. By inhibiting Keap1 function, this probe enhances the transcription of antioxidant response elements, promoting cellular defense against oxidative stress. It is valuable for research on oxidative stress-related diseases, drug discovery targeting the Nrf2 pathway, and studying cellular mechanisms involved in stress responses. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
