Product Data Sheet
Indole-4-carboxaldehyde
Catalog No. A79580
Indole-4-carboxaldehyde functions as an NF-κB activator. This compound demonstrates the ability to attenuate the expression of inflammatory-related genes, including TNF-α and IFN-γ, in HepG2 cells, without exhibiting cytotoxic effects. Additionally, it reduces the formation of advanced glycation end products (AGEs) induced by methylglyoxal (MGO) and decreases the expression of the receptor for RAGE. Indole-4-carboxaldehyde is a valuable reagent for studies focused on hepatic steatosis and related inflammatory pathways.
Chemical Information
| Catalog Num | A79580 |
|---|---|
| M. Wt | 145.16 |
| Formula | C9H7NO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1074-86-8 |
| Synonyms | |
| SMILES | O=CC1=CC=CC2=C1C=CN2 |
Biological Activity
| Description | Indole-4-carboxaldehyde functions as an NF-κB activator. This compound demonstrates the ability to attenuate the expression of inflammatory-related genes, including TNF-α and IFN-γ, in HepG2 cells, without exhibiting cytotoxic effects. Additionally, it reduces the formation of advanced glycation end products (AGEs) induced by methylglyoxal (MGO) and decreases the expression of the receptor for RAGE. Indole-4-carboxaldehyde is a valuable reagent for studies focused on hepatic steatosis and related inflammatory pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
