Product Data Sheet
Karacoline
Catalog No. A79596
Karacoline is a diterpene alkaloid derived from the plant Aconitum kusnezoffii that modulates the NF-κB signaling pathway. This compound plays a significant role in reducing the degradation of the extracellular matrix (ECM), making it valuable for research into intervertebral disc degeneration (IDD) and related conditions. Its ability to influence ECM stability positions Karacoline as a candidate for studying therapeutic interventions in degenerative disc diseases.
Chemical Information
| Catalog Num | A79596 |
|---|---|
| M. Wt | 377.52 |
| Formula | C22H35NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 39089-30-0 |
| Synonyms | |
| SMILES | O[C@@H]1C23C4C([C@]5(O)[C@]6([H])[C@@]3([H])C[C@@]([C@@H](OC)C5)([H])[C@@H]6O)C[C@]2([H])[C@@](CN4CC)(C)CC1 |
Biological Activity
| Description | Karacoline is a diterpene alkaloid derived from the plant Aconitum kusnezoffii that modulates the NF-κB signaling pathway. This compound plays a significant role in reducing the degradation of the extracellular matrix (ECM), making it valuable for research into intervertebral disc degeneration (IDD) and related conditions. Its ability to influence ECM stability positions Karacoline as a candidate for studying therapeutic interventions in degenerative disc diseases. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
