Product Data Sheet
NF-κB-IN-8
Catalog No. A79634
NF-κB-IN-8 is a selective NF-κB inhibitor that competitively antagonizes lipopolysaccharide (LPS) binding to MD-2. This compound effectively reduces the expression of inflammatory mediators, making it a valuable tool for studying inflammatory responses. Additionally, NF-κB-IN-8 has been shown to inhibit alkaline phosphatase (ALP) activity. It is particularly relevant for research into inflammation-related conditions, such as acute lung injury (ALI).
Chemical Information
| Catalog Num | A79634 |
|---|---|
| M. Wt | 399.44 |
| Formula | C24H21N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2924565-59-1 |
| Synonyms | |
| SMILES | COC1=CC=CC(COC2=CC=C(C=C2)/C=C/C(NC3=NC4=C(N3)C=CC=C4)=O)=C1 |
Biological Activity
| Description | NF-κB-IN-8 is a selective NF-κB inhibitor that competitively antagonizes lipopolysaccharide (LPS) binding to MD-2. This compound effectively reduces the expression of inflammatory mediators, making it a valuable tool for studying inflammatory responses. Additionally, NF-κB-IN-8 has been shown to inhibit alkaline phosphatase (ALP) activity. It is particularly relevant for research into inflammation-related conditions, such as acute lung injury (ALI). |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
