Product Data Sheet

Laurotetanine

Catalog No. A79639

main product photo
Laurotetanine is a potent isoquinoline alkaloid functioning as an NF-κB inhibitor. It exhibits anti-asthmatic properties by modulating immune responses, specifically inhibiting IgE and histamine release, alongside reducing inflammatory reactions. Laurotetanine's mechanism involves the downregulation of MUC5AC and NF-κB signaling pathways, making it a valuable tool for research in inflammatory diseases and asthma therapy.
Chemical Information
Catalog NumA79639
M. Wt327.37
FormulaC19H21NO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.128-76-7
Synonyms(+)-Laurotetanine
SMILESOC1=C(C=C2C3=C4C(CCN[C@]4(CC2=C1)[H])=CC(OC)=C3OC)OC
Biological Activity
DescriptionLaurotetanine is a potent isoquinoline alkaloid functioning as an NF-κB inhibitor. It exhibits anti-asthmatic properties by modulating immune responses, specifically inhibiting IgE and histamine release, alongside reducing inflammatory reactions. Laurotetanine's mechanism involves the downregulation of MUC5AC and NF-κB signaling pathways, making it a valuable tool for research in inflammatory diseases and asthma therapy.
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