Product Data Sheet
ABD-350
Catalog No. A79649
ABD-350 is a selective inhibitor of NF-κB, primarily targeting the phosphorylation of the inhibitor of NF-κB. This compound demonstrates key antiresorptive activity by promoting osteoclast apoptosis while preserving osteoblast function, making it effective in preventing ovariectomy-induced bone loss. Its application includes studying osteoclast regulation and potential therapeutic strategies for osteoporosis without interfering with bone formation driven by parathyroid hormone.
Chemical Information
| Catalog Num | A79649 |
|---|---|
| M. Wt | 320.37 |
| Formula | C19H22F2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1117772-52-7 |
| Synonyms | |
| SMILES | OC(CCCCCO)C1=CC=C(C(C)=C1)C2=CC=C(C=C2F)F |
Biological Activity
| Description | ABD-350 is a selective inhibitor of NF-κB, primarily targeting the phosphorylation of the inhibitor of NF-κB. This compound demonstrates key antiresorptive activity by promoting osteoclast apoptosis while preserving osteoblast function, making it effective in preventing ovariectomy-induced bone loss. Its application includes studying osteoclast regulation and potential therapeutic strategies for osteoporosis without interfering with bone formation driven by parathyroid hormone. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
