Product Data Sheet
AM-0561
Catalog No. A79652
AM-0561 is a potent NIK inhibitor with a Ki of 0.3 nM, effectively suppressing the activity of the non-canonical NF-κB signaling pathway. By inhibiting NIK, AM-0561 significantly reduces p52 protein levels, which may contribute to the regulation of various cellular processes. This reagent is useful for research applications aimed at understanding NF-κB signaling in inflammation, immune response, and cancer biology.
Chemical Information
| Catalog Num | A79652 |
|---|---|
| M. Wt | 396.85 |
| Formula | C18H13ClN6OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1202764-63-3 |
| Synonyms | |
| SMILES | C[C@](C1=NC=CS1)(C#CC2=CN3C(C4=NC(N)=NC=C4Cl)=CN=C3C=C2)O |
Biological Activity
| Description | AM-0561 is a potent NIK inhibitor with a Ki of 0.3 nM, effectively suppressing the activity of the non-canonical NF-κB signaling pathway. By inhibiting NIK, AM-0561 significantly reduces p52 protein levels, which may contribute to the regulation of various cellular processes. This reagent is useful for research applications aimed at understanding NF-κB signaling in inflammation, immune response, and cancer biology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
