Product Data Sheet

NF-κB-IN-9

Catalog No. A79660

main product photo
NF-κB-IN-9 is a potent inhibitor of nuclear factor kappa B (NF-κB), functioning as a sonosensitizer with an excitation/emission wavelength of 489/628 nm. This compound exhibits significant inhibition of NF-κB signaling pathways, attributed to its dual resveratrol units. NF-κB-IN-9 demonstrates effective anti-tumor activity and exhibits pronounced sonocytotoxicity against various cancer cell lines. Additionally, NF-κB-IN-9 has shown favorable biosafety profiles in xenograft mouse models, making it a valuable tool for cancer research.
Chemical Information
Catalog NumA79660
M. Wt947.15
FormulaC62H50N4O4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3033815-24-3
Synonyms
SMILESCOC1=CC(OC)=CC(/C=C/C2=CC=C(C=C2)N(C3=CC=CC=C3)C4=CC=C(C=C4)C5=CC=C(C6=NSN=C65)C7=CC=C(C=C7)N(C8=CC=CC=C8)C9=CC=C(C=C9)/C=C/C%10=CC(OC)=CC(OC)=C%10)=C1
Biological Activity
DescriptionNF-κB-IN-9 is a potent inhibitor of nuclear factor kappa B (NF-κB), functioning as a sonosensitizer with an excitation/emission wavelength of 489/628 nm. This compound exhibits significant inhibition of NF-κB signaling pathways, attributed to its dual resveratrol units. NF-κB-IN-9 demonstrates effective anti-tumor activity and exhibits pronounced sonocytotoxicity against various cancer cell lines. Additionally, NF-κB-IN-9 has shown favorable biosafety profiles in xenograft mouse models, making it a valuable tool for cancer research.
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SHIPPING AND STORAGE
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