Product Data Sheet
RMC-4529
Catalog No. A79730
RMC-4529 is a potent inhibitor of the mechanistic target of rapamycin (mTOR), demonstrating an IC50 value of 1.0 nM against phosphorylated 4E-BP1 at threonine 37/46 in cellular assays. This compound is valuable for research applications focused on mTOR signaling pathways, potentially impacting studies in cancer, metabolism, and neurodegenerative diseases. Its selectivity and efficacy make it a useful tool for investigating the role of mTOR in various biological processes.
Chemical Information
| Catalog Num | A79730 |
|---|---|
| M. Wt | 1771.14 |
| Formula | C90H139N13O23 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2250059-27-7 |
| Synonyms | |
| SMILES | NC1=C2C(C3=CC=C(OC(N)=N4)C4=C3)=NN(C2=NC=N1)CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCN5C=C(N=N5)CO/N=C6[C@@H]([C@@H](/C(C)=C/[C@H]([C@@H](C[C@@](OC([C@@]7([H])N(CCCC7)C(C([C@@]8(O[C@](CC[C@H]8C)([H])C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@H]/6C)C)OC)O)=O)=O)=O)([H])[C@H](C)C[C@H]9C[C@H]([C@@H](CC9)O)OC)OC)C)O)OC)=O |
Biological Activity
| Description | RMC-4529 is a potent inhibitor of the mechanistic target of rapamycin (mTOR), demonstrating an IC50 value of 1.0 nM against phosphorylated 4E-BP1 at threonine 37/46 in cellular assays. This compound is valuable for research applications focused on mTOR signaling pathways, potentially impacting studies in cancer, metabolism, and neurodegenerative diseases. Its selectivity and efficacy make it a useful tool for investigating the role of mTOR in various biological processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
