Product Data Sheet
mTOR inhibitor-11
Catalog No. A79736
mTOR Inhibitor-11 is a potent inhibitor of the mechanistic target of rapamycin (mTOR), exhibiting an IC50 of 21 nM for phosphorylated S6 ribosomal protein. This compound also demonstrates inhibitory activity against checkpoint kinase 1 (pCHK1) and phosphodiesterase 4D (PDE4D), with IC50 values of 17.2 μM and 17.0 μM, respectively. mTOR Inhibitor-11 is suitable for research on central nervous system (CNS) diseases, facilitating studies into neurodegenerative conditions and other related disorders.
Chemical Information
| Catalog Num | A79736 |
|---|---|
| M. Wt | 394.47 |
| Formula | C21H26N6O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3033409-32-1 |
| Synonyms | |
| SMILES | C[C@@H]1COCCN1C2=C3N=C(C4=NC=CC=C4)NC3=NC(N5[C@@H](C)COCC5)=C2 |
Biological Activity
| Description | mTOR Inhibitor-11 is a potent inhibitor of the mechanistic target of rapamycin (mTOR), exhibiting an IC50 of 21 nM for phosphorylated S6 ribosomal protein. This compound also demonstrates inhibitory activity against checkpoint kinase 1 (pCHK1) and phosphodiesterase 4D (PDE4D), with IC50 values of 17.2 μM and 17.0 μM, respectively. mTOR Inhibitor-11 is suitable for research on central nervous system (CNS) diseases, facilitating studies into neurodegenerative conditions and other related disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
