PF-06465603
Catalog No. A79763

PF-06465603 is a potent and selective ATP-competitive inhibitor targeting the mTOR pathway. This compound serves as a valuable research tool for studying the regulation of cell growth, proliferation, and survival through mTOR signaling. As a metabolite of PF-04691502, PF-06465603 features a terminal carboxylic acid structure, further facilitating investigations into its biological activity and therapeutic potential in various diseases, including cancer and metabolic disorders.
Chemical Information
| Catalog Num | A79763 |
|---|---|
| M. Wt | 439.46 |
| Formula | C22H25N5O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1431626-44-6 |
| Synonyms | |
| SMILES | O=C(O)CO[C@@H]1CC[C@@H](N(C2=NC(N)=NC(C)=C2C=C3C4=CC=C(OC)N=C4)C3=O)CC1 |
Biological Activity
| Description | PF-06465603 is a potent and selective ATP-competitive inhibitor targeting the mTOR pathway. This compound serves as a valuable research tool for studying the regulation of cell growth, proliferation, and survival through mTOR signaling. As a metabolite of PF-04691502, PF-06465603 features a terminal carboxylic acid structure, further facilitating investigations into its biological activity and therapeutic potential in various diseases, including cancer and metabolic disorders. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


