Product Data Sheet
mTOR inhibitor-16
Catalog No. A79765
mTOR inhibitor-16 (Compound 9f) is a selective inhibitor of the mechanistic target of rapamycin (mTOR). It demonstrates potent inhibitory activity against mTOR and PI3K-α, with IC50 values of 1.25 nM and 82 nM, respectively. This compound effectively inhibits the proliferation of LNCaP prostate cancer cells, with an IC50 of 140 nM, making it a valuable tool for cancer research and studies involving the mTOR signaling pathway.
Chemical Information
| Catalog Num | A79765 |
|---|---|
| M. Wt | 457.55 |
| Formula | C25H23N5O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1144075-42-2 |
| Synonyms | |
| SMILES | O=C(NC1=CC=C(C2=NC3=C(C(N4CC5OC(CC5)C4)=N2)SC=C3)C=C1)NC6=CC=CC=C6 |
Biological Activity
| Description | mTOR inhibitor-16 (Compound 9f) is a selective inhibitor of the mechanistic target of rapamycin (mTOR). It demonstrates potent inhibitory activity against mTOR and PI3K-α, with IC50 values of 1.25 nM and 82 nM, respectively. This compound effectively inhibits the proliferation of LNCaP prostate cancer cells, with an IC50 of 140 nM, making it a valuable tool for cancer research and studies involving the mTOR signaling pathway. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
