Product Data Sheet

MIPS-21335

Catalog No. A79790

main product photo
MIPS-21335 is a selective inhibitor of PI3KC2α, exhibiting an IC50 value of 7 nM. Additionally, it demonstrates inhibition of PI3KC2β, p110α, p110β, and p110δ, with corresponding IC50 values of 43, 140, 386, and 742 nM. MIPS-21335 exhibits significant antithrombotic effects and is valuable for research into cardiovascular and metabolic diseases, including thrombosis and hyperlipidemia.
Chemical Information
Catalog NumA79790
M. Wt487.47
FormulaC24H21N7O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2569296-51-9
Synonyms
SMILESCOC1=C2N=C(N3CCN=C3C2=CC=C1OCC4=CC([N+]([O-])=O)=CC=C4)NC(C5=CN=C(C=C5)N)=O
Biological Activity
DescriptionMIPS-21335 is a selective inhibitor of PI3KC2α, exhibiting an IC50 value of 7 nM. Additionally, it demonstrates inhibition of PI3KC2β, p110α, p110β, and p110δ, with corresponding IC50 values of 43, 140, 386, and 742 nM. MIPS-21335 exhibits significant antithrombotic effects and is valuable for research into cardiovascular and metabolic diseases, including thrombosis and hyperlipidemia.
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