Product Data Sheet
AS-041164
Catalog No. A79805
AS-041164 is a selective inhibitor of the PI3Kγ isoform, demonstrating a potent inhibitory effect with an IC50 of 70 nM. This compound exhibits significantly reduced activity against other isoforms, including PI3Kα, PI3Kβ, and PI3Kδ, with IC50 values of 240 nM, 1.45 μM, and 1.70 μM, respectively. AS-041164 is recognized for its anti-inflammatory properties and is applicable in research focused on inflammation-related pathways and diseases.
Chemical Information
| Catalog Num | A79805 |
|---|---|
| M. Wt | 249.24 |
| Formula | C11H7NO4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 6318-41-8 |
| Synonyms | |
| SMILES | O=C(N1)/C(SC1=O)=C/C2=CC=C3C(OCO3)=C2 |
Biological Activity
| Description | AS-041164 is a selective inhibitor of the PI3Kγ isoform, demonstrating a potent inhibitory effect with an IC50 of 70 nM. This compound exhibits significantly reduced activity against other isoforms, including PI3Kα, PI3Kβ, and PI3Kδ, with IC50 values of 240 nM, 1.45 μM, and 1.70 μM, respectively. AS-041164 is recognized for its anti-inflammatory properties and is applicable in research focused on inflammation-related pathways and diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
