Product Data Sheet
MIPS-9922
Catalog No. A79806
MIPS-9922 is a potent and selective inhibitor of PI3Kβ, exhibiting an IC50 of 63 nM. This compound demonstrates over 30-fold higher potency for PI3Kβ compared to PI3Kδ. MIPS-9922 effectively disrupts PI3K-mediated activation of platelet glycoprotein αIIbβ3 and platelet adhesion in vitro, making it a valuable tool for studying anti-platelet and anti-thrombotic activities in research applications.
Chemical Information
| Catalog Num | A79806 |
|---|---|
| M. Wt | 563.60 |
| Formula | C28H31F2N9O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1416956-33-6 |
| Synonyms | |
| SMILES | O=C(N1CCN(C2=NC(N3C4=CC=CC=C4N=C3C(F)F)=NC(N5CCOCC5)=N2)CC1)[C@@H](N)CC6=CC=CC=C6 |
Biological Activity
| Description | MIPS-9922 is a potent and selective inhibitor of PI3Kβ, exhibiting an IC50 of 63 nM. This compound demonstrates over 30-fold higher potency for PI3Kβ compared to PI3Kδ. MIPS-9922 effectively disrupts PI3K-mediated activation of platelet glycoprotein αIIbβ3 and platelet adhesion in vitro, making it a valuable tool for studying anti-platelet and anti-thrombotic activities in research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
