Product Data Sheet

Nemiralisib succinate

Catalog No. A79873

main product photo
Nemiralisib succinate is a potent and selective inhibitor of phosphoinositide 3-kinase delta (PI3Kδ), exhibiting a pKi of 9.9. This compound demonstrates significant anti-inflammatory effects and is utilized in research applications focusing on immune response modulation and cancer therapy. Its specificity for PI3Kδ makes it an important tool for investigating pathways involved in various diseases, particularly those associated with hematological malignancies and autoimmune disorders.
Chemical Information
Catalog NumA79873
M. Wt558.63
FormulaC30H34N6O5
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1364799-98-3
SynonymsGSK2269557 succinate
SMILESCC(N1CCN(CC2=CN=C(C3=CC(C4=CC=CC5=C4C=CN5)=CC6=C3C=NN6)O2)CC1)C.O=C(CCC(O)=O)O
Biological Activity
DescriptionNemiralisib succinate is a potent and selective inhibitor of phosphoinositide 3-kinase delta (PI3Kδ), exhibiting a pKi of 9.9. This compound demonstrates significant anti-inflammatory effects and is utilized in research applications focusing on immune response modulation and cancer therapy. Its specificity for PI3Kδ makes it an important tool for investigating pathways involved in various diseases, particularly those associated with hematological malignancies and autoimmune disorders.
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SHIPPING AND STORAGE
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