Product Data Sheet

PI3Kδ-IN-18

Catalog No. A79876

main product photo
PI3Kδ-IN-18 is a highly selective inhibitor of the phosphoinositide 3-kinase delta (PI3Kδ) with an IC50 value below 0.1 nM. This compound demonstrates potent inhibitory activity, making it a valuable tool for research applications focused on autoimmune diseases and related signaling pathways. Its ability to modulate PI3Kδ activity allows for the exploration of therapeutic strategies targeting immune cell functionality and inflammation.
Chemical Information
Catalog NumA79876
M. Wt611.55
FormulaC27H32N8O4Se
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3019965-38-6
Synonyms
SMILESCOC1=NC=C(C2=CC=C(N=CN=C3N[C@@H]4CN(C([C@@H](NC(OC(C)(C)C)=O)C[Se]C)=O)CC4)C3=N2)C=C1C#N
Biological Activity
DescriptionPI3Kδ-IN-18 is a highly selective inhibitor of the phosphoinositide 3-kinase delta (PI3Kδ) with an IC50 value below 0.1 nM. This compound demonstrates potent inhibitory activity, making it a valuable tool for research applications focused on autoimmune diseases and related signaling pathways. Its ability to modulate PI3Kδ activity allows for the exploration of therapeutic strategies targeting immune cell functionality and inflammation.
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SHIPPING AND STORAGE
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