Product Data Sheet

GNE-293

Catalog No. A79897

main product photo
GNE-293 is a selective inhibitor of phosphoinositide 3-kinase delta (PI3Kδ), demonstrating an IC50 of 4.38 nM. This compound exhibits favorable pharmacokinetic properties, making it suitable for in vitro and in vivo studies. GNE-293 is particularly relevant for research into asthma, rheumatoid arthritis, and various inflammatory disorders.
Chemical Information
Catalog NumA79897
M. Wt580.70
FormulaC28H36N8O4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1354955-67-1
Synonyms
SMILESCC(C)C1=NC(C=CC=C2)=C2N1C3=NC4=C(N=C(OC5CN(C6CCS(CC6)(=O)=O)C5)N4C)C(N7CCOCC7)=N3
Biological Activity
DescriptionGNE-293 is a selective inhibitor of phosphoinositide 3-kinase delta (PI3Kδ), demonstrating an IC50 of 4.38 nM. This compound exhibits favorable pharmacokinetic properties, making it suitable for in vitro and in vivo studies. GNE-293 is particularly relevant for research into asthma, rheumatoid arthritis, and various inflammatory disorders.
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