Product Data Sheet
JQ-1 carboxylic acid-PEG3-C2-NH2
Catalog No. A79986
JQ-1 carboxylic acid-PEG3-C2-NH2 is an E3 ligase ligand-linker conjugate designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates targeted protein degradation by promoting the interaction between E3 ligases and specific substrates, thereby enabling the selective modulation of protein levels within cells. Its utility in creating PROTACs highlights its vital role in bivalent ligand design and drug development for therapeutic applications.
Chemical Information
| Catalog Num | A79986 |
|---|---|
| M. Wt | 575.12 |
| Formula | C27H35ClN6O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2098790-24-8 |
| Synonyms | |
| SMILES | NCCOCCOCCOCCNC(C[C@@H]1N=C(C2=CC=C(Cl)C=C2)C3=C(SC(C)=C3C)N4C(C)=NN=C14)=O |
Biological Activity
| Description | JQ-1 carboxylic acid-PEG3-C2-NH2 is an E3 ligase ligand-linker conjugate designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates targeted protein degradation by promoting the interaction between E3 ligases and specific substrates, thereby enabling the selective modulation of protein levels within cells. Its utility in creating PROTACs highlights its vital role in bivalent ligand design and drug development for therapeutic applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
