Product Data Sheet
(S,R,S)-AHPC-phenol-C4-NH2 dihydrochloride
Catalog No. A79994
(S,R,S)-AHPC-phenol-C4-NH2 dihydrochloride serves as an E3 ligase ligand-linker conjugate, featuring the (S,R,S)-AHPC VHL ligand integrated with a linker utilized in PROTAC technology. This compound facilitates targeted protein degradation, enhancing research applications in targeted therapy and chemical biology. Its utility in developing PROTACs makes it a valuable reagent for studying E3 ligase activity and pathway modulation in various biological contexts.
Chemical Information
| Catalog Num | A79994 |
|---|---|
| M. Wt | 632.64 |
| Formula | C28H43Cl2N5O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2376990-26-8 |
| Synonyms | VH032-phenol-C4-NH2 dihydrochloride |
| SMILES | [H]Cl.[H]Cl.CC(N[C@H](C(N1C[C@@H](C[C@H]1C(NCC2=CC=C(C=C2OCCCCN)C3=C(N=CS3)C)=O)O)=O)C(C)(C)C)=O |
Biological Activity
| Description | (S,R,S)-AHPC-phenol-C4-NH2 dihydrochloride serves as an E3 ligase ligand-linker conjugate, featuring the (S,R,S)-AHPC VHL ligand integrated with a linker utilized in PROTAC technology. This compound facilitates targeted protein degradation, enhancing research applications in targeted therapy and chemical biology. Its utility in developing PROTACs makes it a valuable reagent for studying E3 ligase activity and pathway modulation in various biological contexts. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
