Product Data Sheet
Thalidomide-Piperazine-Piperidine hydrochloride
Catalog No. A80001
Thalidomide-Piperazine-Piperidine hydrochloride is an E3 ligase ligand-linker conjugate designed for use in targeted protein degradation applications. This compound combines a thalidomide-derived cereblon ligand with a piperazine-piperidine linker, enabling the development of PROTAC molecules. It plays a crucial role in modulating protein levels within cellular systems and may be employed for research into therapeutic strategies that harness the ubiquitin-proteasome pathway.
Chemical Information
| Catalog Num | A80001 |
|---|---|
| M. Wt | 461.94 |
| Formula | C22H28ClN5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2599846-44-1 |
| Synonyms | |
| SMILES | O=C1NC(C(CC1)N2C(C3=CC=C(N4CCN(C5CCNCC5)CC4)C=C3C2=O)=O)=O.Cl |
Biological Activity
| Description | Thalidomide-Piperazine-Piperidine hydrochloride is an E3 ligase ligand-linker conjugate designed for use in targeted protein degradation applications. This compound combines a thalidomide-derived cereblon ligand with a piperazine-piperidine linker, enabling the development of PROTAC molecules. It plays a crucial role in modulating protein levels within cellular systems and may be employed for research into therapeutic strategies that harness the ubiquitin-proteasome pathway. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
