Product Data Sheet
(S,R,S)-AHPC-PEG5-Boc
Catalog No. A80014
(S,R,S)-AHPC-PEG5-Boc is an E3 ligase ligand-linker conjugate designed for targeted protein degradation. This compound combines the (S,R,S)-AHPC variant of the VHL ligand with a polyethylene glycol (PEG) linker to facilitate the efficient ubiquitination of Cdc20. Its primary application lies in the development of targeted therapeutic strategies aimed at modulating protein levels within cellular systems. This compound is ideal for use in drug discovery research focusing on E3 ligase-mediated degradation.
Chemical Information
| Catalog Num | A80014 |
|---|---|
| M. Wt | 807.01 |
| Formula | C40H62N4O11S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2923734-82-9 |
| Synonyms | |
| SMILES | CC(C)(C)[C@@H](C(N1C[C@@H](C[C@H]1C(NCC2=CC=C(C=C2)C3=C(N=CS3)C)=O)O)=O)NC(CCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O)=O |
Biological Activity
| Description | (S,R,S)-AHPC-PEG5-Boc is an E3 ligase ligand-linker conjugate designed for targeted protein degradation. This compound combines the (S,R,S)-AHPC variant of the VHL ligand with a polyethylene glycol (PEG) linker to facilitate the efficient ubiquitination of Cdc20. Its primary application lies in the development of targeted therapeutic strategies aimed at modulating protein levels within cellular systems. This compound is ideal for use in drug discovery research focusing on E3 ligase-mediated degradation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
