Product Data Sheet
Desamino lenalidomide-acetylene-C2-NH2 TFA
Catalog No. A80026
Desamino lenalidomide-acetylene-C2-NH2 TFA is an E3 ligand-linker conjugate designed to target cereblon (CRBN) for targeted protein degradation applications. This compound serves as a crucial component in the synthesis of proteolysis-targeting chimeras (PROTACs), facilitating the selective degradation of specific proteins within cells. Its unique structure enables effective recruitment of the E3 ligase, thereby expanding research potential in therapeutic strategies aimed at modulating protein levels for various biological studies.
Chemical Information
| Catalog Num | A80026 |
|---|---|
| M. Wt | 425.36 |
| Formula | C19H18F3N3O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3065251-37-5 |
| Synonyms | |
| SMILES | O=C1NC(C(CC1)N2C(C3=C(C2)C(C#CCCN)=CC=C3)=O)=O.OC(C(F)(F)F)=O |
Biological Activity
| Description | Desamino lenalidomide-acetylene-C2-NH2 TFA is an E3 ligand-linker conjugate designed to target cereblon (CRBN) for targeted protein degradation applications. This compound serves as a crucial component in the synthesis of proteolysis-targeting chimeras (PROTACs), facilitating the selective degradation of specific proteins within cells. Its unique structure enables effective recruitment of the E3 ligase, thereby expanding research potential in therapeutic strategies aimed at modulating protein levels for various biological studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
