Product Data Sheet
Glutarimide-Isoindolinone-NH-PEG2-COOH
Catalog No. A80027
Glutarimide-Isoindolinone-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that targets cereblon, facilitating the development of PROTAC (Proteolysis Targeting Chimeras) technology. This compound enables the recruitment of E3 ligases for the selective degradation of specific proteins, making it invaluable for studying protein homeostasis and therapeutic intervention. Its application extends to research in targeted protein degradation and drug discovery, enhancing the efficacy of protein-targeted approaches.
Chemical Information
| Catalog Num | A80027 |
|---|---|
| M. Wt | 419.43 |
| Formula | C20H25N3O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2803827-03-2 |
| Synonyms | |
| SMILES | O=C1C2=CC=C(C=C2CN1C3C(NC(CC3)=O)=O)NCCOCCOCCC(O)=O |
Biological Activity
| Description | Glutarimide-Isoindolinone-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that targets cereblon, facilitating the development of PROTAC (Proteolysis Targeting Chimeras) technology. This compound enables the recruitment of E3 ligases for the selective degradation of specific proteins, making it invaluable for studying protein homeostasis and therapeutic intervention. Its application extends to research in targeted protein degradation and drug discovery, enhancing the efficacy of protein-targeted approaches. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
