Product Data Sheet
Pomalidomide-PEG6-C2-COOH
Catalog No. A80031
Pomalidomide-PEG6-C2-COOH is an E3 ligase ligand-linker conjugate that features the cereblon-binding Pomalidomide compound and a six-unit polyethylene glycol (PEG) linker. This reagent is designed for use in PROTAC (Proteolysis Targeting Chimera) technology, facilitating targeted protein degradation. It serves as a valuable tool for researchers exploring the modulation of E3 ligase activity and studying the implications of targeted protein degradation in various therapeutic contexts.
Chemical Information
| Catalog Num | A80031 |
|---|---|
| M. Wt | 609.62 |
| Formula | C28H39N3O12 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2225148-49-0 |
| Synonyms | Pomalidomide-PEG6-COOH |
| SMILES | O=C(CCOCCOCCOCCOCCOCCOCCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)O |
Biological Activity
| Description | Pomalidomide-PEG6-C2-COOH is an E3 ligase ligand-linker conjugate that features the cereblon-binding Pomalidomide compound and a six-unit polyethylene glycol (PEG) linker. This reagent is designed for use in PROTAC (Proteolysis Targeting Chimera) technology, facilitating targeted protein degradation. It serves as a valuable tool for researchers exploring the modulation of E3 ligase activity and studying the implications of targeted protein degradation in various therapeutic contexts. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
