Product Data Sheet
(S,R,S)-AHPC-PEG2-C4-Cl
Catalog No. A80034
(S,R,S)-AHPC-PEG2-C4-Cl is an E3 ligase ligand-linker conjugate designed for targeted protein degradation applications. This compound features the (S,R,S)-AHPC derivative, coupled with a 13-atom-length halogen-linked alkyl/ether-based linker. Its ability to induce the degradation of target proteins, such as GFP-HaloTag7, makes it a valuable tool for researchers investigating E3 ligase-mediated pathways and protein homeostasis in cellular models.
Chemical Information
| Catalog Num | A80034 |
|---|---|
| M. Wt | 651.26 |
| Formula | C32H47ClN4O6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1835705-57-1 |
| Synonyms | VH032-PEG2-C4-Cl; VHL Ligand-Linker Conjugates 7; E3 ligase Ligand-Linker Conjugates 10 |
| SMILES | O=C([C@H]1N(C([C@H](C(C)(C)C)NC(COCCOCCCCCCCl)=O)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2 |
Biological Activity
| Description | (S,R,S)-AHPC-PEG2-C4-Cl is an E3 ligase ligand-linker conjugate designed for targeted protein degradation applications. This compound features the (S,R,S)-AHPC derivative, coupled with a 13-atom-length halogen-linked alkyl/ether-based linker. Its ability to induce the degradation of target proteins, such as GFP-HaloTag7, makes it a valuable tool for researchers investigating E3 ligase-mediated pathways and protein homeostasis in cellular models. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
