Product Data Sheet

Pomalidomide-PEG5-C2-NH2 hydrochloride

Catalog No. A80041

main product photo
Pomalidomide-PEG5-C2-NH2 hydrochloride is a Pomalidomide derivative functioning as a ligand for cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound is instrumental in the design of proteolysis-targeting chimeras (PROTACs) through its conjugation with other proteins via a linker. Its applications extend to targeted protein degradation studies and the exploration of CRBN-mediated pathways in cellular models.
Chemical Information
Catalog NumA80041
M. Wt573.04
FormulaC25H37ClN4O9
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2357117-23-6
Synonyms
SMILESO=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCOCCOCCOCCN)=CC=C3)=O)=O.Cl
Biological Activity
DescriptionPomalidomide-PEG5-C2-NH2 hydrochloride is a Pomalidomide derivative functioning as a ligand for cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound is instrumental in the design of proteolysis-targeting chimeras (PROTACs) through its conjugation with other proteins via a linker. Its applications extend to targeted protein degradation studies and the exploration of CRBN-mediated pathways in cellular models.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.