Product Data Sheet
Desamino lenalidomide-acetylene-C2-NH2
Catalog No. A80063
Desamino lenalidomide-acetylene-C2-NH2 is an E3 ligase ligand-linker conjugate designed to engage cereblon (CRBN) for targeted protein degradation. This compound serves as a crucial component for the synthesis of proteolysis-targeting chimeras (PROTACs), facilitating the selective degradation of proteins by the ubiquitin-proteasome system. Its unique structure enables researchers to explore novel therapeutic strategies and efficacy in various biological contexts.
Chemical Information
| Catalog Num | A80063 |
|---|---|
| M. Wt | 311.34 |
| Formula | C17H17N3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2138440-40-9 |
| Synonyms | |
| SMILES | O=C1NC(=O)C(N2C(=O)C=3C=CC=C(C#CCCN)C3C2)CC1 |
Biological Activity
| Description | Desamino lenalidomide-acetylene-C2-NH2 is an E3 ligase ligand-linker conjugate designed to engage cereblon (CRBN) for targeted protein degradation. This compound serves as a crucial component for the synthesis of proteolysis-targeting chimeras (PROTACs), facilitating the selective degradation of proteins by the ubiquitin-proteasome system. Its unique structure enables researchers to explore novel therapeutic strategies and efficacy in various biological contexts. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
