Product Data Sheet
(S,R,S)-AHPC-C10-NH2 dihydrochloride
Catalog No. A80071
(S,R,S)-AHPC-C10-NH2 dihydrochloride is a specialized E3 ligase ligand-linker conjugate, incorporating the (S,R,S)-AHPC-derived VHL ligand. This compound functions as a key component in the development of BET-targeted PROTACs, facilitating targeted protein degradation in cellular systems. Its application in chemical biology allows for the exploration of protein function through enhanced specificity for E3 ligase engagement, making it a valuable reagent for researchers investigating protein modulation mechanisms.
Chemical Information
| Catalog Num | A80071 |
|---|---|
| M. Wt | 686.78 |
| Formula | C33H53Cl2N5O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2341796-75-4 |
| Synonyms | VH032-C10-NH2 dihydrochloride |
| SMILES | NCCCCCCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O)=O.Cl.Cl |
Biological Activity
| Description | (S,R,S)-AHPC-C10-NH2 dihydrochloride is a specialized E3 ligase ligand-linker conjugate, incorporating the (S,R,S)-AHPC-derived VHL ligand. This compound functions as a key component in the development of BET-targeted PROTACs, facilitating targeted protein degradation in cellular systems. Its application in chemical biology allows for the exploration of protein function through enhanced specificity for E3 ligase engagement, making it a valuable reagent for researchers investigating protein modulation mechanisms. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
