Product Data Sheet
Pomalidomide-amido-C4-amido-C6-NH-Boc
Catalog No. A80080
Pomalidomide-amido-C4-amido-C6-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that employs the Pomalidomide-derived cereblon ligand for targeted protein degradation. This compound is designed to enhance the specificity and efficacy of PROTAC (Proteolysis Targeting Chimera) technology, facilitating the targeted ubiquitination and subsequent degradation of selected proteins. Its applications include investigating cellular pathways and therapeutic strategies in various diseases, including cancer.
Chemical Information
| Catalog Num | A80080 |
|---|---|
| M. Wt | 599.68 |
| Formula | C30H41N5O8 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2435808-02-7 |
| Synonyms | Cereblon Ligand-Linker Conjugates 21; E3 Ligase Ligand-Linker Conjugates 54 |
| SMILES | O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NC(CCCCC(NCCCCCCNC(OC(C)(C)C)=O)=O)=O)=O |
Biological Activity
| Description | Pomalidomide-amido-C4-amido-C6-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that employs the Pomalidomide-derived cereblon ligand for targeted protein degradation. This compound is designed to enhance the specificity and efficacy of PROTAC (Proteolysis Targeting Chimera) technology, facilitating the targeted ubiquitination and subsequent degradation of selected proteins. Its applications include investigating cellular pathways and therapeutic strategies in various diseases, including cancer. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
