Product Data Sheet
Thalidomide-O-C5-azide
Catalog No. A80107
Thalidomide-O-C5-azide is a specialized E3 ubiquitin ligase ligand-linker conjugate, derived from the CRBN inhibitor Thalidomide. This compound features an azide group capable of participating in copper-catalyzed azide-alkyne cycloaddition reactions, making it suitable for use in the synthesis of PROTACs. Thalidomide-O-C5-azide facilitates targeted protein degradation, making it a valuable tool in chemical biology and therapeutic research applications.
Chemical Information
| Catalog Num | A80107 |
|---|---|
| M. Wt | 385.37 |
| Formula | C18H19N5O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2411098-96-7 |
| Synonyms | |
| SMILES | [N-]=[N+]=NCCCCCOC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O |
Biological Activity
| Description | Thalidomide-O-C5-azide is a specialized E3 ubiquitin ligase ligand-linker conjugate, derived from the CRBN inhibitor Thalidomide. This compound features an azide group capable of participating in copper-catalyzed azide-alkyne cycloaddition reactions, making it suitable for use in the synthesis of PROTACs. Thalidomide-O-C5-azide facilitates targeted protein degradation, making it a valuable tool in chemical biology and therapeutic research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
