Product Data Sheet
Pomalidomide-C9-Br
Catalog No. A80116
Pomalidomide-C9-Br is an E3 ligase ligand-linker conjugate designed for the synthesis of PROTAC EGFR degrader 15, a targeted protein degradation agent. This compound exhibits significant anti-cancer activity by promoting the degradation of epidermal growth factor receptor (EGFR) through the proteasome pathway. The use of Pomalidomide-C9-Br in research applications may accelerate the development of novel therapeutics aimed at treating EGFR-driven malignancies.
Chemical Information
| Catalog Num | A80116 |
|---|---|
| M. Wt | 506.39 |
| Formula | C23H28BrN3O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2545963-23-1 |
| Synonyms | |
| SMILES | O=C(N1)CCC(N2C(C(C(NC(CCCCCCCCCBr)=O)=CC=C3)=C3C2=O)=O)C1=O |
Biological Activity
| Description | Pomalidomide-C9-Br is an E3 ligase ligand-linker conjugate designed for the synthesis of PROTAC EGFR degrader 15, a targeted protein degradation agent. This compound exhibits significant anti-cancer activity by promoting the degradation of epidermal growth factor receptor (EGFR) through the proteasome pathway. The use of Pomalidomide-C9-Br in research applications may accelerate the development of novel therapeutics aimed at treating EGFR-driven malignancies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
