Product Data Sheet
Lenalidomide 4'-alkyl-C3-azide
Catalog No. A80123
Lenalidomide 4'-alkyl-C3-azide is a click chemical reagent that incorporates an azide group into lenalidomide, facilitating the synthesis of PROTACs. As an orally active immunomodulator, lenalidomide acts as a ligand for the ubiquitin E3 ligase cereblon (CRBN). This compound is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with alkyne-containing molecules, as well as strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN groups, thereby enabling versatile modifications in chemical biology research.
Chemical Information
| Catalog Num | A80123 |
|---|---|
| M. Wt | 342.35 |
| Formula | C16H18N6O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2399455-71-9 |
| Synonyms | |
| SMILES | [N-]=[N+]=NCCCNC1=CC=CC2=C1CN(C3C(NC(CC3)=O)=O)C2=O |
Biological Activity
| Description | Lenalidomide 4'-alkyl-C3-azide is a click chemical reagent that incorporates an azide group into lenalidomide, facilitating the synthesis of PROTACs. As an orally active immunomodulator, lenalidomide acts as a ligand for the ubiquitin E3 ligase cereblon (CRBN). This compound is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with alkyne-containing molecules, as well as strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN groups, thereby enabling versatile modifications in chemical biology research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
