Product Data Sheet
(S,R,S)-AHPC-C3-NH2 dihydrochloride
Catalog No. A80163
(S,R,S)-AHPC-C3-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate, incorporating the VH032-based VHL ligand and a linker utilized in PROTAC (proteolysis-targeting chimera) technology. This compound serves as a critical building block in the synthesis of various PROTACs, including UNC6852, which is a bivalent chemical degrader specifically targeting EED. (S,R,S)-AHPC-C3-NH2 dihydrochloride facilitates investigations into targeted protein degradation, offering valuable insights into protein regulation and potential therapeutic strategies.
Chemical Information
| Catalog Num | A80163 |
|---|---|
| M. Wt | 588.59 |
| Formula | C26H39Cl2N5O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2564467-25-8 |
| Synonyms | VH032-C3-NH2 dihydrochloride |
| SMILES | NCCCC(N[C@@H](C(C)(C)C)C(N1[C@H](C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O)=O.[H]Cl.[H]Cl |
Biological Activity
| Description | (S,R,S)-AHPC-C3-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate, incorporating the VH032-based VHL ligand and a linker utilized in PROTAC (proteolysis-targeting chimera) technology. This compound serves as a critical building block in the synthesis of various PROTACs, including UNC6852, which is a bivalent chemical degrader specifically targeting EED. (S,R,S)-AHPC-C3-NH2 dihydrochloride facilitates investigations into targeted protein degradation, offering valuable insights into protein regulation and potential therapeutic strategies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
