Product Data Sheet
E3 Ligase Ligand-linker Conjugate 54
Catalog No. A80178
E3 Ligase Ligand-Linker Conjugate 54 is a conjugate composed of Thalidomide and a specific linker, designed to target the E3 ligase Cereblon (CRBN). This compound facilitates the recruitment of CRBN, serving as a crucial intermediate in the development of PROTAC (Proteolysis Targeting Chimeras) molecules. E3 Ligase Ligand-Linker Conjugate 54 is valuable for research focused on targeted protein degradation and E3 ligase modulation, enhancing the understanding of cellular protein homeostasis.
Chemical Information
| Catalog Num | A80178 |
|---|---|
| M. Wt | 539.62 |
| Formula | C28H37N5O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2229725-33-9 |
| Synonyms | |
| SMILES | O=C1NC(CCC1N2C(C3=C(C=CC(N4CCC(CC4)CN5CCN(CC5)C(OC(C)(C)C)=O)=C3)C2=O)=O)=O |
Biological Activity
| Description | E3 Ligase Ligand-Linker Conjugate 54 is a conjugate composed of Thalidomide and a specific linker, designed to target the E3 ligase Cereblon (CRBN). This compound facilitates the recruitment of CRBN, serving as a crucial intermediate in the development of PROTAC (Proteolysis Targeting Chimeras) molecules. E3 Ligase Ligand-Linker Conjugate 54 is valuable for research focused on targeted protein degradation and E3 ligase modulation, enhancing the understanding of cellular protein homeostasis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
