Product Data Sheet
Lenalidomide-amide-pimelic acid
Catalog No. A80180
Lenalidomide-amide-pimelic acid serves as an E3 ligase ligand-linker conjugate, incorporating the Lenalidomide-derived CRBN ligand and a specialized linker. This compound is essential for the synthesis of PROTAC MNK1 degrader-1, facilitating targeted protein degradation via the ubiquitin-proteasome pathway. Its application enhances research into targeted therapies and the modulation of gene expression through protein degradation.
Chemical Information
| Catalog Num | A80180 |
|---|---|
| M. Wt | 401.41 |
| Formula | C20H23N3O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2353496-83-8 |
| Synonyms | |
| SMILES | O=C(CCCCCC(O)=O)NC1=CC=CC2=C1CN(C2=O)C3C(NC(CC3)=O)=O |
Biological Activity
| Description | Lenalidomide-amide-pimelic acid serves as an E3 ligase ligand-linker conjugate, incorporating the Lenalidomide-derived CRBN ligand and a specialized linker. This compound is essential for the synthesis of PROTAC MNK1 degrader-1, facilitating targeted protein degradation via the ubiquitin-proteasome pathway. Its application enhances research into targeted therapies and the modulation of gene expression through protein degradation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
