Product Data Sheet
CDLI-5
Catalog No. A80190
CDLI-5 is a cereblon (CRBN) degrader-linker conjugate designed for the synthesis of cereblon degrader antibody conjugates (cDACs). This compound enables targeted protein degradation through the recruitment of E3 ligases to specific substrates, facilitating effective modulation of protein levels. CDLI-5 serves as a valuable tool in research applications focused on targeted therapies and the development of novel anticancer strategies.
Chemical Information
| Catalog Num | A80190 |
|---|---|
| M. Wt | 1480.59 |
| Formula | C73H83F2N15O15S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3047549-85-6 |
| Synonyms | |
| SMILES | CS(CC(C=C12)=C(C(NCCCCCCCNC3=C4C(C(N(C5C(N(C(CC5)=O)CNC(OCC6=CC=C(C=C6)NC([C@H](CCCNC(N)=O)NC(C7(CCC7)C(NCCCCCN8C(C=CC8=O)=O)=O)=O)=O)=O)=O)C4)=O)=CC=C3)=O)C=C2N(C9=C(C=C(C=N9)F)F)CC%10=CNC%11=C%10C1=CN(C)C%11=O)(=O)=O |
Biological Activity
| Description | CDLI-5 is a cereblon (CRBN) degrader-linker conjugate designed for the synthesis of cereblon degrader antibody conjugates (cDACs). This compound enables targeted protein degradation through the recruitment of E3 ligases to specific substrates, facilitating effective modulation of protein levels. CDLI-5 serves as a valuable tool in research applications focused on targeted therapies and the development of novel anticancer strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
