Product Data Sheet
Thalidomide-4-piperidineacetaldehyde
Catalog No. A80195
Thalidomide-4-piperidineacetaldehyde is an E3 ligase ligand-linker conjugate that engages specific E3 ligases for targeted protein degradation. This reagent serves as a critical component in the synthesis of proteolysis-targeting chimera (PROTAC) H122, facilitating the selective elimination of proteins of interest. Its application supports research in protein regulation and dynamics, with implications for therapeutic development in various disease models.
Chemical Information
| Catalog Num | A80195 |
|---|---|
| M. Wt | 383.40 |
| Formula | C20H21N3O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2222115-36-6 |
| Synonyms | |
| SMILES | O=C(CC1)NC(C1N(C2=O)C(C(C2=C3)=CC=C3N(CC4)CCC4CC=O)=O)=O |
Biological Activity
| Description | Thalidomide-4-piperidineacetaldehyde is an E3 ligase ligand-linker conjugate that engages specific E3 ligases for targeted protein degradation. This reagent serves as a critical component in the synthesis of proteolysis-targeting chimera (PROTAC) H122, facilitating the selective elimination of proteins of interest. Its application supports research in protein regulation and dynamics, with implications for therapeutic development in various disease models. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
