Product Data Sheet

Pomalidomide 5'-piperazine-4-methylpiperidine

Catalog No. A80200

main product photo
Pomalidomide 5'-piperazine-4-methylpiperidine functions as an E3 ligase ligand-linker conjugate, facilitating targeted protein degradation. This compound is instrumental in the synthesis of PROTACs, including the development of PROTAC EGFR degrader 13. Its unique structural properties enable the targeted modulation of protein levels, making it valuable for research in therapeutic strategies that leverage the ubiquitin-proteasome system.
Chemical Information
Catalog NumA80200
M. Wt439.51
FormulaC23H29N5O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2229725-28-2
Synonyms
SMILESO=C1NC(C(CC1)N2C(C3=CC=C(N4CCN(CC5CCNCC5)CC4)C=C3C2=O)=O)=O
Biological Activity
DescriptionPomalidomide 5'-piperazine-4-methylpiperidine functions as an E3 ligase ligand-linker conjugate, facilitating targeted protein degradation. This compound is instrumental in the synthesis of PROTACs, including the development of PROTAC EGFR degrader 13. Its unique structural properties enable the targeted modulation of protein levels, making it valuable for research in therapeutic strategies that leverage the ubiquitin-proteasome system.
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SHIPPING AND STORAGE
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