Product Data Sheet
(S,S,S)-VH032-cyclopropane-F-C4-aldehyde
Catalog No. A80206
(S,S,S)-VH032-cyclopropane-F-C4-aldehyde is an E3 ligase ligand-linker conjugate designed for use in the synthesis of PROTAC compounds, specifically cis-VZ185. This reagent facilitates targeted protein degradation by engaging with the ubiquitin-proteasome system, making it a valuable tool for researchers investigating protein modulation and degradation pathways. Its unique structure allows for precise conjugation in drug discovery applications focused on cancer and other diseases influenced by protein dysregulation.
Chemical Information
| Catalog Num | A80206 |
|---|---|
| M. Wt | 616.74 |
| Formula | C31H41FN4O6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2306193-97-3 |
| Synonyms | |
| SMILES | [H]C(CCCCOC1=C(CNC([C@H]2N(C([C@@H](NC(C3(F)CC3)=O)C(C)(C)C)=O)C[C@@H](O)C2)=O)C=CC(C4=C(N=CS4)C)=C1)=O |
Biological Activity
| Description | (S,S,S)-VH032-cyclopropane-F-C4-aldehyde is an E3 ligase ligand-linker conjugate designed for use in the synthesis of PROTAC compounds, specifically cis-VZ185. This reagent facilitates targeted protein degradation by engaging with the ubiquitin-proteasome system, making it a valuable tool for researchers investigating protein modulation and degradation pathways. Its unique structure allows for precise conjugation in drug discovery applications focused on cancer and other diseases influenced by protein dysregulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
