Product Data Sheet
(S,R,S)-AHPC-C2-NH2
Catalog No. A80238
(S,R,S)-AHPC-C2-NH2 is an E3 ligase ligand-linker conjugate that incorporates the VH032-derived VHL ligand, designed for applications in targeted protein degradation via PROTAC technology. This compound facilitates the recruitment of E3 ligases to target proteins, enabling efficient ubiquitination and subsequent proteasomal degradation. Its use in research can enhance the understanding of protein dynamics and assist in the development of therapeutics aimed at regulating protein levels in various disease contexts.
Chemical Information
| Catalog Num | A80238 |
|---|---|
| M. Wt | 501.64 |
| Formula | C25H35N5O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2241643-69-4 |
| Synonyms | |
| SMILES | O=C(N(C[C@@H]1O)[C@@H](C1)C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(CCN)=O |
Biological Activity
| Description | (S,R,S)-AHPC-C2-NH2 is an E3 ligase ligand-linker conjugate that incorporates the VH032-derived VHL ligand, designed for applications in targeted protein degradation via PROTAC technology. This compound facilitates the recruitment of E3 ligases to target proteins, enabling efficient ubiquitination and subsequent proteasomal degradation. Its use in research can enhance the understanding of protein dynamics and assist in the development of therapeutics aimed at regulating protein levels in various disease contexts. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
