Product Data Sheet
E3 Ligase Ligand-linker Conjugate 125
Catalog No. A80298
E3 Ligase Ligand-linker Conjugate 125 is a specialized conjugate designed to engage E3 ligases for targeted protein degradation. This reagent facilitates the synthesis of PROTAC IRAK4 degrader-12, enabling selective degradation of IRAK4, which is implicated in various signaling pathways and inflammatory processes. It serves as a valuable tool in chemical biology and therapeutic research, particularly in the study of targeted protein modulation and novel drug development strategies.
Chemical Information
| Catalog Num | A80298 |
|---|---|
| M. Wt | 421.45 |
| Formula | C22H23N5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2918284-14-5 |
| Synonyms | |
| SMILES | O=C(CN1CCNCC1)NC2=CC=CC3=C4C(C5C(NC(CC5)=O)=O)=NOC4=CC=C32 |
Biological Activity
| Description | E3 Ligase Ligand-linker Conjugate 125 is a specialized conjugate designed to engage E3 ligases for targeted protein degradation. This reagent facilitates the synthesis of PROTAC IRAK4 degrader-12, enabling selective degradation of IRAK4, which is implicated in various signaling pathways and inflammatory processes. It serves as a valuable tool in chemical biology and therapeutic research, particularly in the study of targeted protein modulation and novel drug development strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
