Product Data Sheet
Thalidomide 5-pyrrolidine-CHO
Catalog No. A80305
Thalidomide 5-pyrrolidine-CHO is a conjugate designed for E3 ubiquitin ligase ligand-linker applications. This compound facilitates protein degradation by linking to E3 ligases, enabling targeted protein modulation. It serves as a valuable tool in the development and synthesis of novel bivalent degraders, such as NRX-0492. Researchers can utilize this compound for studies related to targeted therapeutics and protein homeostasis regulation.
Chemical Information
| Catalog Num | A80305 |
|---|---|
| M. Wt | 355.34 |
| Formula | C18H17N3O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2416132-74-4 |
| Synonyms | |
| SMILES | O=C[C@H]1CN(C2=CC3=C(C(N(C(CC4)C(NC4=O)=O)C3=O)=O)C=C2)CC1 |
Biological Activity
| Description | Thalidomide 5-pyrrolidine-CHO is a conjugate designed for E3 ubiquitin ligase ligand-linker applications. This compound facilitates protein degradation by linking to E3 ligases, enabling targeted protein modulation. It serves as a valuable tool in the development and synthesis of novel bivalent degraders, such as NRX-0492. Researchers can utilize this compound for studies related to targeted therapeutics and protein homeostasis regulation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
