Product Data Sheet
(S,R,S)-AHPC-C7-amine dihydrochloride
Catalog No. A80325
(S,R,S)-AHPC-C7-amine dihydrochloride functions as an E3 ligase ligand-linker conjugate, integrating the VH032-based VHL ligand with a tailored linker. This compound is specifically designed for use in PROTAC (proteolysis-targeting chimeras) applications, targeting the estrogen-related receptor α (ERRα) for degradation. Its unique structure enables enhanced selective degradation of ERRα, making it a valuable tool for research in targeted protein degradation and related cellular pathways.
Chemical Information
| Catalog Num | A80325 |
|---|---|
| M. Wt | 644.70 |
| Formula | C30H47Cl2N5O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2415256-17-4 |
| Synonyms | VH032-C7-amine dihydrochloride |
| SMILES | NCCCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)=O)=O.Cl.Cl |
Biological Activity
| Description | (S,R,S)-AHPC-C7-amine dihydrochloride functions as an E3 ligase ligand-linker conjugate, integrating the VH032-based VHL ligand with a tailored linker. This compound is specifically designed for use in PROTAC (proteolysis-targeting chimeras) applications, targeting the estrogen-related receptor α (ERRα) for degradation. Its unique structure enables enhanced selective degradation of ERRα, making it a valuable tool for research in targeted protein degradation and related cellular pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
