Product Data Sheet
E3 Ligase Ligand-linker Conjugate 221
Catalog No. A80370
E3 Ligase Ligand-Linker Conjugate 221 is designed to selectively engage E3 ligases through a CRBN-based ligand and a linker component. This conjugate facilitates the synthesis of PROTACs (Proteolysis Targeting Chimeras), enabling targeted protein degradation for various therapeutic applications. It serves as a valuable tool in chemical research focused on modulating protein levels within biological systems.
Chemical Information
| Catalog Num | A80370 |
|---|---|
| M. Wt | 380.79 |
| Formula | C15H17ClN6O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2222117-40-8 |
| Synonyms | |
| SMILES | O=C1NC(C(CC1)N2C(C3=NC=C(N4CCNCC4)N=C3C2=O)=O)=O.Cl |
Biological Activity
| Description | E3 Ligase Ligand-Linker Conjugate 221 is designed to selectively engage E3 ligases through a CRBN-based ligand and a linker component. This conjugate facilitates the synthesis of PROTACs (Proteolysis Targeting Chimeras), enabling targeted protein degradation for various therapeutic applications. It serves as a valuable tool in chemical research focused on modulating protein levels within biological systems. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
