Product Data Sheet
Thalidomide-4-O-C6-Br
Catalog No. A80378
Thalidomide-4-O-C6-Br is an E3 ligase ligand-linker conjugate that utilizes a thalidomide-derived CRBN ligand, designed for applications in PROTAC technology. This compound is intended for the selective degradation of target proteins by facilitating the formation of protein degrader molecules, such as PROTAC EZH2 Degrader-12. Its unique structure allows for the targeted modulation of protein levels, making it a valuable tool for research into targeted protein degradation and related therapeutic strategies.
Chemical Information
| Catalog Num | A80378 |
|---|---|
| M. Wt | 437.28 |
| Formula | C19H21BrN2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2653338-53-3 |
| Synonyms | |
| SMILES | BrCCCCCCOC1=C2C(N(C3CCC(NC3=O)=O)C(C2=CC=C1)=O)=O |
Biological Activity
| Description | Thalidomide-4-O-C6-Br is an E3 ligase ligand-linker conjugate that utilizes a thalidomide-derived CRBN ligand, designed for applications in PROTAC technology. This compound is intended for the selective degradation of target proteins by facilitating the formation of protein degrader molecules, such as PROTAC EZH2 Degrader-12. Its unique structure allows for the targeted modulation of protein levels, making it a valuable tool for research into targeted protein degradation and related therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
