Product Data Sheet
E3 ligase Ligand 63-N-CH2-Ph-O-CH3
Catalog No. A80385
E3 Ligase Ligand 63-N-CH2-Ph-O-CH3 is an E3 ligase ligand-linker conjugate that incorporates a CRBN-based ligand and a flexible linker. This compound is designed for the synthesis of PROTACs (proteolysis-targeting chimeras), facilitating targeted protein degradation. Its unique structure supports the recruitment of E3 ligases to target proteins, enabling efficient modulation of protein levels in various research applications, including cancer therapy and cellular signaling studies.
Chemical Information
| Catalog Num | A80385 |
|---|---|
| M. Wt | 458.31 |
| Formula | C21H20BrN3O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2357109-91-0 |
| Synonyms | |
| SMILES | O=C1N(C=2C(Br)=CC=CC2N1C3C(=O)N(C(=O)CC3)CC4=CC=C(OC)C=C4)C |
Biological Activity
| Description | E3 Ligase Ligand 63-N-CH2-Ph-O-CH3 is an E3 ligase ligand-linker conjugate that incorporates a CRBN-based ligand and a flexible linker. This compound is designed for the synthesis of PROTACs (proteolysis-targeting chimeras), facilitating targeted protein degradation. Its unique structure supports the recruitment of E3 ligases to target proteins, enabling efficient modulation of protein levels in various research applications, including cancer therapy and cellular signaling studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
