Product Data Sheet
Pomalidomide-C2-amide-C5-azide
Catalog No. A80388
Pomalidomide-C2-amide-C5-azide is an E3 ligase linker conjugate that targets selected proteins for ubiquitination and degradation via the PROTAC (proteolysis-targeting chimera) approach. This compound demonstrates notable antiproliferative activity and can be utilized in research applications focused on CDK9 modulation. Its design allows for the synthesis of potent PROTAC molecules, advancing studies in targeted protein degradation and cancer therapeutics.
Chemical Information
| Catalog Num | A80388 |
|---|---|
| M. Wt | 455.47 |
| Formula | C21H25N7O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2732859-29-7 |
| Synonyms | |
| SMILES | [N-]=[N+]=NCCCCCC(NCCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)=O |
Biological Activity
| Description | Pomalidomide-C2-amide-C5-azide is an E3 ligase linker conjugate that targets selected proteins for ubiquitination and degradation via the PROTAC (proteolysis-targeting chimera) approach. This compound demonstrates notable antiproliferative activity and can be utilized in research applications focused on CDK9 modulation. Its design allows for the synthesis of potent PROTAC molecules, advancing studies in targeted protein degradation and cancer therapeutics. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
