Product Data Sheet
Thalidomide-5-piperazine-azetidine
Catalog No. A80416
Thalidomide-5-piperazine-azetidine is an E3 ligase ligand-linker conjugate that incorporates a CRBN-based ligand attached to a versatile linker. This compound is designed to facilitate the synthesis of PROTACs (proteolysis targeting chimeras), enabling targeted degradation of specific proteins within cellular systems. Key applications include the investigation of protein function and the development of novel therapeutic strategies for diseases associated with dysregulated protein levels.
Chemical Information
| Catalog Num | A80416 |
|---|---|
| M. Wt | 397.44 |
| Formula | C20H23N5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2680530-60-1 |
| Synonyms | |
| SMILES | O=C1NC(=O)C(N2C(=O)C3=CC=C(C=C3C2=O)N4CCN(CC4)C5CNC5)CC1 |
Biological Activity
| Description | Thalidomide-5-piperazine-azetidine is an E3 ligase ligand-linker conjugate that incorporates a CRBN-based ligand attached to a versatile linker. This compound is designed to facilitate the synthesis of PROTACs (proteolysis targeting chimeras), enabling targeted degradation of specific proteins within cellular systems. Key applications include the investigation of protein function and the development of novel therapeutic strategies for diseases associated with dysregulated protein levels. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
